Discovery of Virus

 

 

In 1884, Charles Chamberland found out that the agent responsible for rabies passes through the porcelain filter.

In those times, any agent which caused disease was termed as virus. The term filterable and non-filterable virus was used then.
In 1892, Ivanowski discovered that the agent responsible for Tobacco mosaic disease does not pass through the filter and bacteria free filtrate still caused the disease.

After that, it was discovered that filtrate caused many diseases.

In 1935, Stanley purified filterable agents and was successful in crystallizing tobacco mosaic virus and found out that they contained only proteins and nucleic acid.
This led to the discovery of viruses.
Structure of Virus

Virion

Infectious part consists of the genome and capsid.

Genome

Nucleic acid. either DNA or RNA. Forms central core

Capsid

Protein coat. made of protein subunits called capsomeres. Adenovirus has 252 capsomeres while heroes virus has 162 capsomeres.

 

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